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  • Paulina Villaseca
    Centro de Excelencia en Biomedicina de Magallanes (CEBIMA) Universidad de Magallanes – Pontificia Universidad Católica de Chile


  1. Ruan X, Mueck AO, Beer AM, Naser B, Pickartz S. Review. Benefit-risk profile of black cohosh (isopropanolic Cimicifuga racemosa extract) with and without St John’s wort in breast cancer patients. Climacteric 2019;22(4):339-347.
  2. Beer AM, Neff A. Differentiated evaluation of extract-specific evidence on Cimicifuga racemosa’s efficacy and safety for climacteric complaints. Evid Based Complement Alternat Med 2013;2013: 860602
  3. Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database of Systematic Reviews 2012, Issue 9. Art. No.: CD007244.
  4. Chen SN, Fabricant DS, Lu ZZ, Fong HHS, Farnsworth NR. Cimiracemosides I-P, new 9,19-cyclolanostane triterpene glycosides from Cimicifuga racemose. J Nat Prod 2002;65(10):1391-7.
  5. Powell SL, Gödecke T, Nikolic D, et al. In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent. J Agric Food Chem 2008;56(24):11718-26.
  6. Davis VL, Jayo MJ, Ho A, et al. Black cohosh increases metastatic mammary cancer in transgenic mice expressing c-erbB2. Cancer Res 2008;68:8377–83.
  7. European Union Herbal Monograph on Cimicifuga racemosa (L.) Nutt., rhizoma EMA/HMPC/48745/2017.
  8. Community Herbal Monograph on Hypericum Perforatum L., Herba (Well-Established Medicinal Use). Doc Ref: EMA/HMPC/101304/2008.
  9. NIH. US National Library of Medicine. National Center for Biotechnology Information. PubChem. Hyperforin.

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