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Impacto de las intervenciones tópicas sobre la microbiota vaginal y el metaboloma en mujeres postmenopáusicas: un análisis secundario de un ensayo clínico aleatorio

Resumen Recientemente Srinivasan et al. [1] publicaron los resultados de un análisis secundario post-hoc pre-especificado de un ensayo clínico aleatorio (ECA) multicéntrico de 12 semanas de duración en mujeres postmenopáusicas con síntomas genitourinarios de moderados a graves, con el fin de comparar las modificaciones en la diversidad y la composición de la microbiota vaginal, el metaboloma y… Read More

Los efectos del ejercicio sobre los síntomas vasomotores en las mujeres menopáusicas: una revisión sistemática y un meta-análisis

Resumen Liu y colaboradores [1] informaron recientemente de una revisión sistemática y un meta-análisis que evaluó el potencial del ejercicio estructurado para aliviar la frecuencia subjetiva y la severidad de los síntomas vasomotores (SVM). Para ello, los autores buscaron en cuatro bases de datos para identificar ensayos controlados aleatorios (ECA) que evaluaran el efecto del… Read More

Vaginal laser therapy versus hyaluronic acid suppositories for women with symptoms of urogenital atrophy after treatment for breast cancer: A randomized controlled trial

Summary Urogenital atrophy affects more than half of women after breast cancer (BC) and in this population there is reluctance to use local estrogen. Therapies free of hormones such as intravaginal laser and hyaluronic acid suppositories have shown to produce symptom relief in women with BC and urogenital atrophy. However, they have not been tested… Read More

Menopause impacts the human brain structure, connectivity, energy metabolism, and amyloid‑beta deposition

Summary The menopause transition (MT) is a neuro-endocrine process that impacts the aging trajectories of multiple organ and systems including the brain. The MT occurs over time and is characterized by clinically defined stages with specific neurological symptoms. However, the way this process impacts the human brain remains unclear. Recently Mosconi et al. [1] reported a multi-modality… Read More

Disruption of Sleep continuity during the Perimenopause - is there an association with female reproductive hormone?

Summary Sleep problems are frequently encountered during the menopausal transition, which have been related to various factors and can impair female quality of life [1]; however, direct relation with hormonal changes of the menopausal transition is still unclear. Recently Coborn et al. [2] reported a study that aimed at determining the association between female reproductive hormones and… Read More

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: recommendation statement of the US Preventive Services Task Force

Summary The US Preventive Services Task Force (USPSTF) published a recommendation on statin use for primary prevention in 2016 [1]. Now the task force has commissioned a new review of the evidence on the benefits and harms of statins as the basis for an update of the 2016 guidelines [2]. There were 26 studies included… Read More

Cow's milk intake and risk of coronary heart disease in Korean postmenopausal women

Summary Numerous publications have reported conflicting results on the association between cow's milk intake and coronary heart disease (CHD). However, studies involving postmenopausal women are very limited. Recently, Ha et al. [1] reported the results of a study that aimed to identify the relationship between cow's milk intake and the risk of CHD in postmenopausal women. For… Read More

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