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Prevention of osteoporosis-related fractures has been a major preventive goal during the last years and different interventions have been recommended. Järvinen and colleagues have carried out a meta-analysis of 33 randomized controlled trials (RCTs) and have demonstrated that current screening strategies and bisphosphonate treatment are ineffective in preventing hip fractures [1]. The available RCTs are heterogeneous and have methodological flaws that hamper the formation of recommendations about antiresorptive treatments, including the general use of calcium and vitamin D supplements. The authors also declared that the dominant approach is not cost-effective in preventing hip fractures and none of the three studies conducted in subjects older than 80 years reported that pharmacologic treatment reduced the hip fracture risk.


  • F. R. Pérez-López
    Department of Obstetrics and Gynecology, University of Zaragoza and Lozano-Blesa University Hospital, Domingo Miral s/n, Zaragoza, Spain
  • I. Ara
    Growth, Exercise, Nutrition and Development (GENUD) Toledo Research Group, University of Castilla-La Mancha, Toledo, Spain


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