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Cell- and tissue-specific sex steroid formation and inactivation in menopausal women: intracrinology

Labrie [1] recently published a review describing that, while DHEA (dehydroepiandrosterone, prasterone) is present in the blood during the whole life of women, the sex steroid precursor DHEA becomes the only source of sex steroids after menopause [2,3], a time when the ovaries have stopped secreting estrogens [3,4], most likely to protect the endometrium [5].… Read More

Body image and depression

With aging, women's bodies undergo changes that can affect body image perception, yet little is known about body image in midlife. In a subset of the SWAN cohort from Chicago, the associations between body image and depressive symptoms were investigated [1]. Body image was measured using the Stunkard Adult Female Figure Rating Scale, and a… Read More

Prevalence of urinary incontinence according to hysterectomy status in the WHI observational study

Urinary incontinence (UI) is a common and frequently overlooked problem in aging women [1,2]. Leaking urine limits daily and working activities, social interaction and sexual intimacy, and therefore severely disrupts quality of life [3]. The relationship between menopause, aging and hysterectomy is complex and still unresolved. While it is clinically appreciated that all these factors… Read More

Energy balance and mortality

The [i]American Journal of Epidemiology[/i] recently published online two studies that are based on data from the Women's Health Initiative Observational Study (WHIOS). The first one creates a platform for the upcoming national US dietary recommendations [1]. Four commonly used diet quality indices – the Healthy Eating Index 2010 (HEI), the Alternative Healthy Eating Index… Read More

Preventive medicine: GYNs or GPs?

From 2007 to 2010, an average of 281,406,600 medical visits occurred annually in the USA according to data from medical records of national representative visits to office-based physicians and visits to outpatient departments. The current study analyzed 63 million preventive care visits, of which 44% were visits to OB/GYNs and 56% were to primary-care doctors… Read More

Long-term persistence in postmenopausal women receiving osteoporosis medications

Chronic pharmacologic treatments have the risk of low adherence and persistence which depend on the disease severity, preventive objectives, co-morbidity, other concurrent medications (polymedication) and adverse events. Wade and colleagues [1] reported follow-up data regarding osteoporosis medication persistence and switching at 24 months and 36 months in postmenopausal women from the cohort of the US… Read More

International Menopause Society

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