A new analysis from the WHI observational study addresses the potential differences in risk for cardiovascular disease (CVD) associated with different doses, formulations and routes of administration of postmenopausal hormone therapy (HT) [1)]. As a reminder, the WHI observational trial was a multicenter, prospective cohort study that was conducted at 40 US sites. Analyses included… Read More
HRT, body mass index and breast cancer risk
Hou and colleagues have addressed the question of different levels of risk of breast cancer under hormone replacement therapy (HRT) according to race, body mass index (BMI) and breast density [1]. Using 1,642,824 screening mammograms, they analyzed 9300 breast cancer cases in postmenopausal women ≥ 45 years from the Breast Cancer Surveillance Consortium (BCSC), a… Read More
Keep your weight – dont miss breakfast
Here is the perception: skipping breakfast increases hunger throughout the day, making people overeat and seek out snacks to compensate for missing that first – and some would say most important – meal of the day. This belief is based on many studies and was not challenged until recently, when Brown and colleagues published their… Read More
Menopausal hormone therapy and prevention of chronic diseases: IMS members react to the recent JAMA paper
Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention. A total of 27,347 postmenopausal women aged 50–79 years were enrolled at 40 US centers to the Women's Health Initiative trial [1]. Women with an intact uterus received conjugated equine estrogens (CEE; 0.625 mg/day) plus medroxyprogesterone… Read More
Menopausal hormone therapy and prevention of chronic diseases: IMS members react to the recent JAMA paper
Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention. A total of 27,347 postmenopausal women aged 50–79 years were enrolled at 40 US centers to the Women's Health Initiative trial [1]. Women with an intact uterus received conjugated equine estrogens (CEE; 0.625 mg/day) plus medroxyprogesterone… Read More
Influence of recency and duration of glucocorticoid use on bone mineral density and risk of fractures
Majunder y colegas han informado recientemente sobre la influencia del uso reciente y la duración de glucocorticoides orales sistémicos sobre la densidad mineral ósea (DMO) y el riesgo de fractura, independientemente de la dosis. Mediante un estudio de cohorte basado en la población y la utilización de un conjunto de datos validados que incluía todos… Read More
Antihypertensives and breast cancer risk
Another potential 'bomb' exploded recently, with the online publication of a study which showed that common therapies for controlling blood pressure may have an effect on the risk for breast cancer [1]. The study, which was observational and retrospective, was based on interviews with breast cancer patients and comparable healthy controls in Seattle, USA. Women… Read More
Bangladesh Menopause Society first AGM - First Report
First report form the Bangladesh Menopause Society of their first AGM and second medical conference - read more »… Read More
Controlling caloric intake and energy expenditure may not be enough to keep weight stable
Whenever one talks about the need to keep optimal weight in order to reduce cardiovascular risk and other health hazards, one will always quote the mantra – eat healthy and stay fit, which means keeping the desired balance between caloric intake and energy expenditure. The standard equation says that 7000 kcal equal 1 kg of… Read More
Endometrial cancer and adipokines
Endometrial cancer is the most prevalent type of female genital tract malignancy in the developed countries. It represents nearly 50% of all new genital cancers in the Western world, surpassing the incidence of cervical cancer. Endometrial cancer is a disease of postmenopausal women (median age 63 years) and 90% of cases occur in patients over… Read More